Sep 2011
Enhancers
Fulai Jin, Yan Li, Bing Ren, Rama Natarajan
Transcription · DOI: 10.4161/trns.2.5.17712 · PMID: 22231119
Publications
Apr 2026
Proinsulin regulators identified with CRISPR screen and in vivo mouse QTL mapping
2026
Map functional insulators with cross-platform Hi-C meta-analysis
Oct 2025
A comprehensive benchmark of single-cell Hi-C embedding tools
Jul 2025
The Somatic Mosaicism across Human Tissues Network
Oct 2024
Heterogeneous enhancer states orchestrate β cell responses to metabolic stress
Sep 2023
Single cell multiomic analysis reveals diabetes-associated β-cell heterogeneity driven by HNF1A.
Jul 2022
DeepLoop robustly maps chromatin interactions from sparse allele-resolved or single-cell Hi-C data at kilobase resolution.
Aug 2021
INFIMA leverages multi-omics model organism data to identify effector genes of human GWAS variants.
Nov 2020
Single-cell lineage analysis reveals extensive multimodal transcriptional control during directed beta-cell differentiation.
Oct 2020
Aberrant methylation underlies insulin gene expression in human insulinoma.
Sep 2020
TWO-SIGMA: A novel two-component single cell model-based association method for single-cell RNA-seq data.
Jun 2020
Robust Hi-C Maps of Enhancer-Promoter Interactions Reveal the Function of Non-coding Genome in Neural Development and Diseases.
Apr 2020
Myt Transcription Factors Prevent Stress-Response Gene Overactivation to Enable Postnatal Pancreatic β Cell Proliferation, Function, and Survival.
Oct 2019
Exploring the Trans-Cleavage Activity of CRISPR-Cas12a (cpf1) for the Development of a Universal Electrochemical Biosensor.
Mar 2019
Single-Cell Heterogeneity Analysis and CRISPR Screen Identify Key β-Cell-Specific Disease Genes.
Aug 2018
Chemical Screening Identifies Enhancers of Mutant Oligodendrocyte Survival and Unmasks a Distinct Pathological Phase in Pelizaeus-Merzbacher Disease.
Dec 2017
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling.
Apr 2015
Epigenetic priming of enhancers predicts developmental competence of hESC-derived endodermal lineage intermediates.
Feb 2015
Integrative analysis of 111 reference human epigenomes.
Dec 2014
CRISPR reveals a distal super-enhancer required for Sox2 expression in mouse embryonic stem cells.
Oct 2013
A high-resolution map of the three-dimensional chromatin interactome in human cells.
May 2013
Epigenomic analysis of multilineage differentiation of human embryonic stem cells.
Mar 2013
RFECS: a random-forest based algorithm for enhancer identification from chromatin state.
Apr 2012
Topological domains in mammalian genomes identified by analysis of chromatin interactions.
Sep 2011
Enhancers
Mar 2011
PU.1 and C/EBP(alpha) synergistically program distinct response to NF-kappaB activation through establishing monocyte specific enhancers.
Jul 2008
Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-kappaB-dependent inflammatory genes. Relevance to diabetes and inflammation.
Nov 2007