Publications
All
2025
A comprehensive benchmark of single-cell Hi-C embedding tools
Nature Communications
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14 Oct 2025
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doi:10.1038/s41467-025-64186-4
2023
Single cell multiomic analysis reveals diabetes-associated β-cell heterogeneity driven by HNF1A.
Nature communications
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05 Sep 2023
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pubmed:37669939
2022
DeepLoop robustly maps chromatin interactions from sparse allele-resolved or single-cell Hi-C data at kilobase resolution.
Nature genetics
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11 Jul 2022
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pubmed:35817982
2021
INFIMA leverages multi-omics model organism data to identify effector genes of human GWAS variants.
Genome biology
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23 Aug 2021
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pubmed:34425882
2020
Single-cell lineage analysis reveals extensive multimodal transcriptional control during directed beta-cell differentiation.
Nature metabolism
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30 Nov 2020
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pubmed:33257854
Aberrant methylation underlies insulin gene expression in human insulinoma.
Nature communications
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15 Oct 2020
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pubmed:33060578
TWO-SIGMA: A novel two-component single cell model-based association method for single-cell RNA-seq data.
Genetic epidemiology
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29 Sep 2020
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pubmed:32989764
Robust Hi-C Maps of Enhancer-Promoter Interactions Reveal the Function of Non-coding Genome in Neural Development and Diseases.
Molecular cell
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26 Jun 2020
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pubmed:32592681
Myt Transcription Factors Prevent Stress-Response Gene Overactivation to Enable Postnatal Pancreatic β Cell Proliferation, Function, and Survival.
Developmental cell
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30 Apr 2020
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pubmed:32359405
2019
Exploring the Trans-Cleavage Activity of CRISPR-Cas12a (cpf1) for the Development of a Universal Electrochemical Biosensor.
Angewandte Chemie (International ed. in English)
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17 Oct 2019
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pubmed:31568601
Single-Cell Heterogeneity Analysis and CRISPR Screen Identify Key β-Cell-Specific Disease Genes.
Cell reports
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12 Mar 2019
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pubmed:30865899
2018
Chemical Screening Identifies Enhancers of Mutant Oligodendrocyte Survival and Unmasks a Distinct Pathological Phase in Pelizaeus-Merzbacher Disease.
Stem cell reports
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23 Aug 2018
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pubmed:30146490
2017
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling.
Nature
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20 Dec 2017
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pubmed:29258295
2015
Epigenetic priming of enhancers predicts developmental competence of hESC-derived endodermal lineage intermediates.
Cell stem cell
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02 Apr 2015
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pubmed:25842977
Integrative analysis of 111 reference human epigenomes.
Nature
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19 Feb 2015
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pubmed:25693563
2014
CRISPR reveals a distal super-enhancer required for Sox2 expression in mouse embryonic stem cells.
PloS one
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08 Dec 2014
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pubmed:25486255
2013
A high-resolution map of the three-dimensional chromatin interactome in human cells.
Nature
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20 Oct 2013
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pubmed:24141950
Epigenomic analysis of multilineage differentiation of human embryonic stem cells.
Cell
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09 May 2013
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pubmed:23664764
RFECS: a random-forest based algorithm for enhancer identification from chromatin state.
PLoS computational biology
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14 Mar 2013
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pubmed:23526891
2012
Topological domains in mammalian genomes identified by analysis of chromatin interactions.
Nature
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11 Apr 2012
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pubmed:22495300
2011
PU.1 and C/EBP(alpha) synergistically program distinct response to NF-kappaB activation through establishing monocyte specific enhancers.
Proceedings of the National Academy of Sciences of the United States of America
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14 Mar 2011
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pubmed:21402921
Enhancers: multi-dimensional signal integrators.
Transcription
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01 Jan 2011
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pubmed:22231119
2008
Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-kappaB-dependent inflammatory genes. Relevance to diabetes and inflammation.
The Journal of biological chemistry
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23 Jul 2008
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pubmed:18650421
2007
Proinflammatory effects of advanced lipoxidation end products in monocytes.
Diabetes
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14 Nov 2007
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pubmed:18003754